Blood clotting and IC'ness?

From: FMAJ1019@aol.com
Date: Sun Sep 10 2000 - 17:33:09 EDT

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    From talk.origins

    A 10-year retrospective literature search in the National Library of
    Medicine (PubMed) on the argument "prekallikrein" yielded some
    interesting results, including some interesting facts about the
    supposedly "irreducibly complex" blood clotting cascade in a variety of
    snake species.

    http://www.ncbi.nlm.nih.gov:80/entrez/query.fcqi?cmd=PubMed&list_uids=23
    41766&dopt=Abstract (Notes on clotting in a Burmese python (Python
    molurus bittatus). Ratnoff, O.D. et al. J Lab Clin Med 1990 v.
    11595):629-635 "...prothrombin could only be demonstrated in trace
    amounts. Similarly, only small amounts of Hageman factor (factor XII)
    and antihemophilic factor (factor VIII) were detected, and none of
    plasma prekallikrein, high molecular weight kininogen, and Christmas
    factor (factor IX). ... Factor VII was not detected."

    http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=PubMed&list_uids=16
    09651&dopt=Abstract (Killikrein-kinin system in the plasma of snakes).
    Picarelli, Z.P. et al, Agents Actions Suppl 1992; 36:271-281. "Whereas
    plasma pf the snakes Waqglerophis merremii (Wm) and Crotalus durissus
    (Cd), were shown to contain factor XII, prekallikrein, kininogen,
    kinanases and a low but definite activation rate of the kinin system,
    the plasmas of Bj [Bothrops jararaca], Bothrops mojeni (Bm) and
    Oxyrophus trigeminus (Ot), yielded only kininogen and kinanases. ...the
    plasma of these species does not possess either factor XII and/or
    prekaillikrein."

    Reduction via evolution? But Behe said these systems were IC! What's
    going on here?

    Jack Sullivan



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