From talk.origins
A 10-year retrospective literature search in the National Library of
Medicine (PubMed) on the argument "prekallikrein" yielded some
interesting results, including some interesting facts about the
supposedly "irreducibly complex" blood clotting cascade in a variety of
snake species.
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcqi?cmd=PubMed&list_uids=23
41766&dopt=Abstract (Notes on clotting in a Burmese python (Python
molurus bittatus). Ratnoff, O.D. et al. J Lab Clin Med 1990 v.
11595):629-635 "...prothrombin could only be demonstrated in trace
amounts. Similarly, only small amounts of Hageman factor (factor XII)
and antihemophilic factor (factor VIII) were detected, and none of
plasma prekallikrein, high molecular weight kininogen, and Christmas
factor (factor IX). ... Factor VII was not detected."
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=PubMed&list_uids=16
09651&dopt=Abstract (Killikrein-kinin system in the plasma of snakes).
Picarelli, Z.P. et al, Agents Actions Suppl 1992; 36:271-281. "Whereas
plasma pf the snakes Waqglerophis merremii (Wm) and Crotalus durissus
(Cd), were shown to contain factor XII, prekallikrein, kininogen,
kinanases and a low but definite activation rate of the kinin system,
the plasmas of Bj [Bothrops jararaca], Bothrops mojeni (Bm) and
Oxyrophus trigeminus (Ot), yielded only kininogen and kinanases. ...the
plasma of these species does not possess either factor XII and/or
prekaillikrein."
Reduction via evolution? But Behe said these systems were IC! What's
going on here?
Nelson:
The clotting cascade requires TPA and it's activator among many other parts
to function. None of the above addresses anything about the parts that make
the clotting cascade irreducibly complex.
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