Re: The *fact* of evolution

From: Tedd Hadley (hadley@reliant.yxi.com)
Date: Fri May 19 2000 - 19:15:18 EDT

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    Cliff Lundberg writes
      in message <4.1.20000519143551.009c94e0@pop.sfo.com>:
    > Bertvan@aol.com wrote:
    >
    > >I am an ardent admirer of Margulis. She once said "Darwinism
    > >will one day be regarded as a quaint 20th century superstition."
    > >or something like that. Has she written something lately?
    > >Do you know a good book or internet material on this "not-so-new
    > >theory of cellular evolution"?

       Here's another quote from Margulis:

    "Biologists have no doubt that evolution occurred. They even know
     what drives it: the growth of any population of organisms beyond
     the ability of the environment to support them, the appearance of
     organisms that have novel genetic traits, and the greater growth
     of some of those variant organisms leading to changed populations
     over time - the process known as natural selection. But biologists
     are still debating the details of how it occurs. The theory of
     evolution, like any other scientific theory, is being continually
     revised and refined.
     
     ... Scientific meetings on these subjects often generate great
     disagreements. These disagreements have been misrepresented to the
     public by creationists as evidence that the theory of evolution is
     in doubt. On the contrary, they are evidence that what is going on
     is the pursuit of science and not the shoring up of dogma."
     
    Farewell To Newton, Einstein, Darwin..., Allen Hammond and Lynn
    Margulis, Science 81, Dec 1981, pp.55-57. Quoted from page 56.

    > No, but I hope someone else here does.
       
       I found the following link which appears to present
       a good background of the theory in layman's terms.

    http://falcon.cc.ukans.edu/~jjmohn/endosymbiosis.htm:

    The gap between eukaryotes, cells with nuclei, and prokaryotes,
    cells which lack nuclei, is considered by many biologists to be
    the most profound missing link in evolutionary history. In an
    attempt to describe the way in which this gap was bridged, scientists
    have proposed the serial endosymbiosis theory (SET). The term
    "endosymbiosis" specifies the relationship between organisms which
    live one within another (symbiont within host) in a mutually
    beneficial relationship. The SET states that the evolution of
    eukaryotes from prokaryotes involved the symbiotic union of several
    previously independent ancestors. According to the theory, these
    ancestors included a host cell, an ancestor of mitochondria, an
    ancestor of chloroplasts, and, more controversially, a prokaryote
    that brought with it the structures that today provide cellular
    motion.

    The idea that the eukaryotic cell is actually a colony of microbes
    was first suggested in the 1920s by American biologist Ivan Wallin
    (Fausto-Sterling 1993). The originator of the modern version of
    the SET is biologist Lynn Margulis. In 1981, Margulis published
    the first edition of her book entitled Symbiosis in Cell Evolution
    in which she proposed that eukaryotic cells originated as communities
    of interacting entities that joined together in a specific order.
    With time, the members of this union became the organelles of a
    single host (Margulis 1993). The organelle progenitors could have
    gained entry into a host cell as undigested prey or as an internal
    parasite after which the combination became mutually beneficial to
    both organisms. As the organisms became more interdependent, an
    obligatory symbiosis evolved.

    ...

    One early and important discovery in support of the SET occurred
    in the laboratory of Kwang W. Jeon, a biologist at the University
    of Tennessee. Jeon witnessed the establishment of an amoeba-bacteria
    symbiosis in which new bacterial symbionts became integrated in
    the host amoeba (Jeon 1991). In 1966, when the bacteria first
    infected the amoebas, they were lethal to their hosts. However, as
    time progressed, some of the infected amoebas survived and became
    dependent on their newly acquired endosymbionts within a few years.
    Jeon was able to prove this dependency by performing nuclei
    transplants between infected amoebas and amoebas lacking the
    bacteria. If left alone, the hybrid amoebas died in a matter of
    days. Yet if he reinfected these hybrids with the once-lethal
    bacteria, the amoebas recovered and once again began to grow
    (Margulis and Sagan 1987). This discovery served to demonstrate
    that endosymbiosis could provide a major mechanism for cellular
    evolution and explain the introduction of new species (Jeon 1991).

    Although some of Margulis' ideas remain controversial, there is
    mounting evidence in support of the SET (Fausto-Sterling 1993).
    The bulk of this evidence serves to defend the notion of an
    endosymbiotic origin of mitochondria and chloroplasts.

    ....

    It has been nearly thirty years since Lynn Margulis first published
    a book on the origin of eukaryotic cells. Since that time, biology
    has undergone extraordinary changes. The most noticeable change is
    the extensive accumulation of sequence data for both nucleic acids
    and proteins. The collection of new data will undoubtedly lead to
    continuous revision of the serial endosymbiosis theory of the origin
    of the eukaryotic cell. Despite the uncertain future, the crucial
    foundation has been laid. Symbiosis is now accepted by the scientific
    community as an important factor in generating evolutionary change.
    The next steps include the development of more elaborate methods
    to interpret genetic and molecular sequence data and the undertaking
    of a fresh look at the fossil record. These tactics might reveal
    significant information concerning one of the most challenging and
    fascinating problems in evolutionary biology, the origin of the
    eukaryotes.



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