Re: RNA.editing.questions

Glenn Morton (GRMorton@gnn.com)
Fri, 26 Jul 1996 20:52:21

In the RNA editing, are certain patterns preferably edited? or do the
changed cytosine appear randomly in sequence? Are there RNA edits of the
other 3 nucleotides?

Having spent the first 6 years of my career in the digital signal
processing part of my profession, one thing I learned was that information
does not appear out of nowhere. Somewhere there must be a set of
instructions for these repairs. If there is truly no instruction for this
in the genome then we are witnessing a miracle where God himself changes
the appropriate cytosines.

Since I don't think God is doing this, I would like to see what is wrong
with the following suggestion. This depends upon the existence of some
info storage location. Lineages which lost the correct sequence but which
also had a fortuitous correction mechanism were able to continue living
and reproducing. Those that didn't have it, died.

Now are there fortuitous, pre-existing correction mechanisms? What about
those that change the cytosine in the 3rd location with no effect on amino
acid sequence? Is that possibly evidence of such a function?

Also, are proteins with proper sequences ever found changed by this RNA
editing?

glenn
Foundation,Fall and Flood
http://members.gnn.com/GRMorton/dmd.htm