Re: rapid variations

Walter ReMine (wjremine@mmm.com)
Sat, 09 Sep 1995 18:41:38 -0500

>I want to make clear that I do not know how many
>nucleotide substitutions are required to make a new allele.

Precisely. Glenn has persistently failed to document this key point. He
merely ASSUMED that alleles typically differ by 6 nucleotides. Here is
Glenn assuming it again:

>The number 6 has been banded around but it may be that there needs
>to be more than 6 and this process must be able to account for all 59
>MHC alleles.

Walter ReMine